Professor and Honorary Consultant in Medical Oncology
0161 446 8106
0161 446 3468
MB ChB MSc FRCP
Cancers of the pancreas, biliary tract (cholangiocarcinoma and gallbladder cancer), liver and neuroendocrine tumours
Prof Valle’s outpatient clinics include a weekly research clinic, a chemotherapy and review clinic and a dedicated neuroendocrine clinic which also includes clinical trials. Multidisciplinary team meetings include attendance at the specialist hepato-pancreato-biliary (HPB) multi-disciplinary team (MDT), held at Central Manchester Foundation Trust; the specialist neuroendocrine MDT and a gastrointestinal radiology meeting (on the alternate weeks). He is also the clinical lead for the European Neuroendocrine Tumour Society (ENETS) Christie Centre of Excellence for neuroendocrine tumours.
Prof Valle is the Chair of the National Cancer Research Institute (NCRI) neuroendocrine tumour sub-group; member of the NCRI upper gastrointestinal clinical studies group; member of the NCRI pancreatic sub-group; and member of the NCRI hepatobiliary sub-group.
Prof Valle was appointed as a Consultant in Medical Oncology at The Christie having completed his training in Medical Oncology in Manchester in 2010. He works within the gastrointestinal disease group and has developed a specialist interest in HPB and NETs.
Major achievements include international recognition for research in the field of biliary tract cancers, particularly through establishing the reference treatment for patients with advanced disease [ABC-02 study, published in the prestigious New Engl J Med in 2010]. This has provided a platform for follow-on studies as well as studies in earlier stages of the disease. He has also been involved in practice changing studies in NETs [also published in New Engl J Med in 2011] and pancreatic cancer [see publication list].
Prof Valle leads and participates in phase Ib to III clinical trials in the field of hepatobiliary cancers (pancreas, biliary tract and hepatocellular carcinoma) and neuroendocrine tumours; he collaborates closely on research with the Cancer Research UK Manchester Institute (formerly the Paterson Institute) laboratories and the Wolfson Molecular Imaging Centre.